Sugi Predict

Sugi Predict / Compounds / SCHEMBL8908555

SCHEMBL8908555

SCHEMBL8908555

CC1(c2ccc(Oc3ccccc3)cc2)OC(=S)N(Nc2ccccc2)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 5/20 0.40
▸ MMP9 P14780 5/20 0.40
▸ MMP3 P08254 1/20 0.40
▸ MMP8 P22894 1/20 0.40
▸ MMP13 P45452 1/20 0.40
▸ MMP1 P03956 1/20 0.37
▸ ADAM17 P78536 1/20 0.37
▸ ALDH1A1 P00352 2/20 0.35
▸ GFER P55789 1/20 0.35
▸ MAPT P10636 2/20 0.35
▸ CYP1A2 P05177 1/20 0.34
▸ PGR P06401 1/20 0.34
▸ HPGD P15428 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ UTS2R Q9UKP6 1/20 0.33
▸ PIM1 P11309 1/20 0.33
▸ EPHX1 P07099 1/20 0.33
▸ HTT P42858 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9370299 0.94 MAPT (0.36) MMP2MMP9MMP3MMP8MMP13
SCHEMBL9370365 0.92 PGR (0.38) MMP2MMP9MMP3MMP8MMP13
SCHEMBL9370810 0.88 CYP1A2 (0.40) ALDH1A1MAPTCYP1A2HPGDMEN1
SCHEMBL9375669 0.88 CYP1A2 (0.40) ALDH1A1MAPTCYP1A2HPGDMEN1
SCHEMBL9374306 0.88 CYP1A2 (0.40) ALDH1A1MAPTCYP1A2HPGDMEN1
Famoxadone SCHEMBL63351 0.88 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
Famoxadone SCHEMBL14128616 0.88 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
Famoxadone SCHEMBL673443 0.88 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
SCHEMBL9408896 0.87 P2RX3 (0.34) MMP2MMP9
Famoxadone SCHEMBL17293878 0.86 MMP2 (0.41) MMP2MMP9MMP3MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393911-B1 Fungicidal oxazolidinones DU PONT (US) 1994-08-31 — — EP claimed
US-5223523-A Agriculture E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-29 — — US claimed
EP-0469061-A1 FUNGICIDAL OXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-02-05 — — EP claimed
WO-1991015480-A1 FUNGICIDAL OXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-17 — — WO claimed
WO-1990012791-A1 FUNGICIDAL OXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-01 — — WO claimed
EP-0393911-A1 Fungicidal oxazolidinones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-24 — — EP claimed
US-4957933-A Fungicidal oxazolidinones E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-18 — — US claimed
JP-9104677-A — — None — — JP disclosed
JP-H09104677-A FUNGICIDAL OXAZOLIDINONES E I DU PONT DE NEMOURS & CO 1997-04-22 — — JP disclosed
US-5356908-A Agriculture E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-18 — — US disclosed
EP-0393911-B1 Fungicidal oxazolidinones DU PONT (US) 1994-08-31 — — EP disclosed
US-5223523-A Agriculture E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-29 — — US disclosed
EP-0469061-A1 FUNGICIDAL OXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-02-05 — — EP disclosed
WO-1991015480-A1 FUNGICIDAL OXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-17 — — WO disclosed
WO-1990012791-A1 FUNGICIDAL OXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-01 — — WO disclosed
EP-0393911-A1 Fungicidal oxazolidinones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-24 — — EP disclosed
US-4957933-A Fungicidal oxazolidinones E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-18 — — US disclosed