SCHEMBL8908799

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8908761	0.86	MAPT (0.63)	KDM4EHTTDDX3XMEN1KMT2A
	SCHEMBL8908778	0.85	DDX3X (0.45)	POLBKDM4EHTTDDX3XMEN1
	SCHEMBL8908800	0.83	CHRNA7 (0.50)	KDM4EHTTDDX3XMEN1KMT2A
	SCHEMBL8910206	0.82	MAPT (0.58)	KDM4EHTTDDX3XMEN1KMT2A
	SCHEMBL8909173	0.82	PDE4B (0.50)	POLBKDM4EDDX3XMEN1KMT2A
	SCHEMBL8909203	0.81	MAPT (0.53)	KDM4EDDX3XMEN1KMT2AMAPT
	SCHEMBL8908762	0.79	CA12 (0.48)	POLBKDM4EDDX3XMEN1KMT2A
	SCHEMBL8908765	0.77	KCNH3 (0.59)	KDM4EDDX3XMEN1KMT2AMAPT
	SCHEMBL8909159	0.76	MAPT (0.48)	KDM4EDDX3XMEN1KMT2AMAPT
	SCHEMBL3052619	0.75	POLB (1.00)	POLBKDM4EHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.