Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256057 | 0.80 | REN (0.56) | RENTSHRP2RX1 | |
| SCHEMBL7276949 | 0.80 | REN (0.56) | RENTSHRP2RX1 | |
| SCHEMBL8909805 | 0.80 | REN (0.56) | RENTSHRP2RX1 | |
| SCHEMBL8908881 | 0.80 | REN (0.41) | RENCTSKP2RX1CTSSEPHX1 | |
| SCHEMBL8908885 | 0.78 | REN (0.42) | RENCTSKCTSLCTSBTSHR | |
| SCHEMBL8909210 | 0.77 | P2RX1 (0.54) | RENP2RX1 | |
| SCHEMBL7339890 | 0.76 | CTSS (0.51) | RENCTSKCTSS | |
| SCHEMBL9800557 | 0.75 | REN (0.61) | RENP2RX1 | |
| SCHEMBL7429514 | 0.73 | REN (0.43) | RENP2RX1 | |
| SCHEMBL7292991 | 0.70 | REN (0.43) | RENP2RX1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |