Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909853 | 0.81 | LTA4H (0.42) | LTA4HTRPM8PTGS1PTGS2SLC1A3 | |
| SCHEMBL8638399 | 0.72 | LTA4H (0.55) | LTA4HRAB9APOLBNPC1SMN1; SMN2 | |
| SCHEMBL8641136 | 0.70 | LTA4H (0.43) | LTA4HRAB9APOLBNPC1HPGD | |
| SCHEMBL8638408 | 0.69 | LTA4H (0.44) | LTA4HRAB9APOLBNPC1HPGD | |
| SCHEMBL10526948 | 0.68 | LTA4H (0.52) | LTA4HRAB9APOLBNPC1HPGD | |
| SCHEMBL8638403 | 0.66 | LTA4H (0.39) | LTA4HRAB9APOLBNPC1HPGD | |
| SCHEMBL8641130 | 0.66 | LTA4H (0.56) | LTA4HRAB9APOLBNPC1SMN1; SMN2 | |
| SCHEMBL9263774 | 0.66 | LTA4H (0.56) | LTA4HRAB9APOLBNPC1HPGD | |
| SCHEMBL546118 | 0.65 | L3MBTL1 (0.57) | LTA4HRAB9APOLBNPC1HPGD | |
| SCHEMBL9495408 | 0.65 | NPC1 (0.58) | RAB9APOLBNPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700816-A | ANTIARTHRITIC AGENTS | G.D. SEARLE & CO. | 1997-12-23 | — | — | US | claimed |