Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909018 | 0.81 | LTA4H (0.43) | LTA4HSLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL8637368 | 0.71 | LTA4H (0.55) | LTA4HSLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL5684056 | 0.71 | LTA4H (0.48) | LTA4HPTGS1PTGS2ALDH1A1TRPM8 | |
| SCHEMBL8640502 | 0.70 | LTA4H (0.43) | LTA4HSLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL8637374 | 0.68 | LTA4H (0.43) | LTA4HSLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL22775084 | 0.67 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1SIRT5ALDH1A1 | |
| SCHEMBL28035078 | 0.65 | TP53 (0.58) | SIRT5ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8637371 | 0.65 | LTA4H (0.39) | LTA4HSLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL8640498 | 0.65 | LTA4H (0.55) | LTA4HSLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL1855435 | 0.64 | LTA4H (0.57) | LTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700816-A | ANTIARTHRITIC AGENTS | G.D. SEARLE & CO. | 1997-12-23 | — | — | US | claimed |