SCHEMBL8909031

SCHEMBL8909031

COc1cc(OC)c(NC(=O)C(/C=N/NO)c2ccccc2)c(OC)c1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7506166 1.00 MEN1 (0.46) MEN1KMT2A
SCHEMBL5797214 0.77 MEN1 (0.51) MEN1KMT2A
SCHEMBL7506148 0.75 MEN1 (0.46) MEN1KMT2A
SCHEMBL7052592 0.74 MEN1 (0.48) MEN1KMT2A
Benzene SCHEMBL7510710 0.73 NPC1 (0.41) MEN1KMT2A
SCHEMBL5772297 0.72 MMP8 (0.58)
SCHEMBL9680327 0.69 KMT2A (0.70) MEN1KMT2A
Acetic Acid SCHEMBL8909148 0.67 RAB9A (0.63) MEN1KMT2A
SCHEMBL18415560 0.66 MAPT (0.51) MEN1KMT2A
SCHEMBL30977634 0.65 CYP3A4 (0.48) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693657-A USEFUL FOR TREATING HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 1997-12-02 US disclosed