SCHEMBL8909039

SCHEMBL8909039

O=S(=O)(O)c1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.43
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
PGAM1 P18669 1/20 0.41
PTGS2 P35354 1/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CASP1 P29466 2/20 0.40
CHAT P28329 1/20 0.40
SNCA P37840 1/20 0.40
TTR P02766 2/20 0.39
FABP4 P15090 1/20 0.39
CCNA2 P20248 1/20 0.39
CDK2 P24941 1/20 0.39
MAPK14 Q16539 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
BCL2L1 Q07817 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10528139 0.89 HNF4A (0.54) HNF4ATSHRSMN1; SMN2FABP4ALDH1A1
SCHEMBL2521857 0.89 PTGS2 (0.44) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL28147663 0.85 TSHR (0.40) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL8368643 0.85 HDAC4 (0.52) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL537547 0.84 AKR1B1 (0.42) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL232659 0.84 CASP1 (0.47) HNF4AHDAC4HDAC2HDAC8HDAC6
Sulfuric Acid SCHEMBL28507654 0.84 HNF4A (0.48) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL29743050 0.84 CASP1 (0.47) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL392931 0.82 TSHR (0.41) HNF4AHDAC4HDAC2HDAC8HDAC6
SCHEMBL30166530 0.82 TSHR (0.41) HNF4AHDAC4HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0550486-B1 PROCESS FOR PRODUCING CONCENTRATED AQUEOUS SOLUTIONS OF ANIONIC AZO DYES HOECHST AG (DE) 1995-02-08 EP claimed
WO-1992006140-A1 PROCESS FOR PRODUCING CONCENTRATED AQUEOUS SOLUTIONS OF ANIONIC AZO DYES HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-16 WO claimed
US-4565546-A Condensation product and use thereof as dispersant for pitch in water slurry NIKKA CHEMICAL INDUSTRY CO. (JP) 1986-01-21 US claimed
EP-0044026-A1 Process for dyeing synthetic fibrous materials HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-20 EP claimed
US-4245996-A Condensation products of terphenylsulphonic acids, naphthalenesulphonic acids, bis-(4-hydroxyphenyl) sulphone and formaldehyde BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US claimed
EP-0019846-A2 Tanning agents of the azo series, their preparation and their use in the simultaneous tanning and dyeing of leather, and preparations containing them BAYER AG (DE) 1980-12-10 EP claimed
US-4118384-A DIAZOTIZATION BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US claimed
US-5656684-A Silanes containing oxalamide functional groups and their use as plastics additives BAYER AG (DE) 1997-08-12 US disclosed
US-5508389-A CARRYING OUT DIAZOTIZATION OR COUPLING IN THE PRESENCE OF AN AUXILLIARY SUCH AS A NAPHTHALENESULFONIC ACID-FORMALDEHYDE CONDENSATION PRODUCT WHICH EXERTS A VISCOSITY-REDUCING EFFECT ON PASTY PHASES HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed
US-5352241-A Process for retanning mineral tanned leathers with aromatic sulphonic acids BAYER AKTIENGESELLSCHAFT (DE) 1994-10-04 US disclosed
US-5279622-A Triazine dyes BAYER AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
EP-0512320-A1 Solid dye preparations with improved water solubility BAYER AG (DE) 1992-11-11 EP disclosed
US-4754020-A ACID IS ION EXCHANGE RESIN, EASY SEPARATION BAYER AKTIENGESELLSCHAFT (DE) 1988-06-28 US disclosed
US-4245996-A Condensation products of terphenylsulphonic acids, naphthalenesulphonic acids, bis-(4-hydroxyphenyl) sulphone and formaldehyde BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
EP-0019846-A2 Tanning agents of the azo series, their preparation and their use in the simultaneous tanning and dyeing of leather, and preparations containing them BAYER AG (DE) 1980-12-10 EP disclosed
EP-0008032-A1 Condensation products from terphenyl-sulphonic acids, naphthalene-sulphonic acids, bis-(4-hydroxyphenyl)-sulphone and formaldehyde, and their use as tanning agents BAYER AG (DE) 1980-02-20 EP disclosed
EP-0008032-A1 Condensation products from terphenyl-sulphonic acids, naphthalene-sulphonic acids, bis-(4-hydroxyphenyl)-sulphone and formaldehyde, and their use as tanning agents BAYER AG (DE) 1980-02-20 EP disclosed
US-4118384-A DIAZOTIZATION BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed
US-3906037-A Formaldehyde condensation products of terphenyl-sulphonic acids BAYER AG 1975-09-16 US disclosed
US-3906037-A Formaldehyde condensation products of terphenyl-sulphonic acids BAYER AG 1975-09-16 US disclosed