Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.43 |
| ▸ | PLAU | P00749 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438863 | 0.93 | F10 (0.48) | PRSS1TP53F2F10 | |
| SCHEMBL8908116 | 0.83 | F10 (0.49) | PRSS1PLAUF2PLGF10 | |
| SCHEMBL8438856 | 0.76 | F10 (0.49) | PRSS1F2F10 | |
| SCHEMBL7358748 | 0.76 | WDR5 (0.50) | PRSS1PLAUF2F10 | |
| SCHEMBL7364511 | 0.75 | F10 (0.57) | PRSS1F2F10 | |
| SCHEMBL8908041 | 0.74 | F10 (0.53) | PRSS1F2F10 | |
| SCHEMBL7366139 | 0.74 | F10 (0.53) | PRSS1PLAUF2PLGKLK1 | |
| SCHEMBL7360668 | 0.72 | F2 (0.54) | PRSS1PLAUF2PLGKLK1 | |
| SCHEMBL8443278 | 0.71 | F10 (0.52) | PRSS1F2F10 | |
| SCHEMBL7359931 | 0.71 | MRGPRX4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | disclosed |