Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | AOC2 | O75106 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547637 | 0.81 | ACHE (0.41) | ALDH1A1PPARGPPARA | |
| SCHEMBL9482061 | 0.79 | POLB (0.43) | SLC6A4PPARGPPARAMAOBMAOA | |
| SCHEMBL366155 | 0.78 | CA4 (0.39) | SLC6A4MAOA | |
| SCHEMBL8909407 | 0.78 | CA4 (0.39) | SLC6A4MAOA | |
| SCHEMBL3575375 | 0.77 | HPGD (0.46) | NFE2L2SLC6A4PPARGPPARA | |
| SCHEMBL4005272 | 0.76 | ALDH1A1 (0.52) | ALDH1A1NFE2L2SLC6A4IDO1TDO2 | |
| SCHEMBL105035 | 0.70 | ALDH1A3 (0.52) | ALDH1A1NFE2L2 | |
| SCHEMBL4071188 | 0.69 | ALDH1A1 (0.50) | ALDH1A1NFE2L2SLC6A4PPARGPPARA | |
| SCHEMBL28937983 | 0.69 | ALDH1A1 (0.48) | ALDH1A1NFE2L2SLC6A4IDO1TDO2 | |
| SCHEMBL29619680 | 0.69 | ALDH1A1 (0.48) | ALDH1A1NFE2L2SLC6A4PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |