Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8909771 | 0.98 | MAOA (0.41) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL7581178 | 0.77 | MAOA (0.38) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL1453422 | 0.74 | MAOA (0.39) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL23331965 | 0.73 | MAOA (0.52) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL7362590 | 0.73 | MAOA (0.52) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL11296841 | 0.73 | MAOA (0.47) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL13901175 | 0.72 | MAPT (0.45) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL1455282 | 0.71 | ALDH1A1 (0.39) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL7238679 | 0.70 | MAOA (0.48) | MAOAMAOBSLC6A4SMN1; SMN2MAPT | |
| SCHEMBL11081702 | 0.70 | MAOA (0.44) | MAOAMAOBSLC6A4SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |