Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 3/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911209 | 0.84 | RARA (0.41) | MEN1KMT2ARARARARBRARG | |
| SCHEMBL28425561 | 0.73 | CA12 (0.57) | MEN1KMT2APOLBGAAMCL1 | |
| SCHEMBL3976009 | 0.73 | MEN1 (0.46) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL17323573 | 0.70 | MEN1 (0.45) | MEN1KMT2AMAPTCYP2C19RARA | |
| SCHEMBL10783918 | 0.69 | MEN1 (0.57) | MEN1KMT2AMCL1ACMSDCYP2C19 | |
| SCHEMBL28589092 | 0.69 | MEN1 (0.53) | MEN1KMT2APOLBMCL1ACMSD | |
| SCHEMBL18155724 | 0.68 | RARB (0.44) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL7165307 | 0.67 | ERN1 (0.43) | MEN1KMT2AMCL1ACMSDMAPT | |
| SCHEMBL3971743 | 0.67 | MCL1 (0.37) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL21038145 | 0.67 | CHRNA1 (0.38) | MEN1KMT2AMCL1ACMSDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686586-A | Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1997-11-11 | — | — | US | disclosed |