Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909355 | 0.84 | MEN1 (0.42) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL8458292 | 0.75 | IKBKB (0.41) | RARALMNAKMT2ACNR2GPR55 | |
| SCHEMBL8458293 | 0.72 | IKBKB (0.39) | RARAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8458442 | 0.72 | IKBKB (0.42) | RARALMNAKMT2AMEN1AVPR2 | |
| SCHEMBL8459014 | 0.71 | CNR2 (0.31) | AVPR2AVPR1ACNR2 | |
| SCHEMBL21194961 | 0.69 | GPR35 (0.43) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL17323573 | 0.67 | MEN1 (0.45) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL4747624 | 0.67 | RARB (0.61) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL3715625 | 0.67 | KMT2A (0.61) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL1082729 | 0.67 | KMT2A (0.61) | RARARARBRARGLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686586-A | Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1997-11-11 | — | — | US | disclosed |