Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280044 | 0.84 | PSIP1 (0.52) | PSIP1HSD11B1CA12CA1CA2 | |
| SCHEMBL778303 | 0.83 | PSIP1 (0.60) | PSIP1HSD11B1POLBLARS1ALDH1A1 | |
| SCHEMBL17624545 | 0.80 | KMT2A (0.49) | ALDH1A1SMN1; SMN2GBA1 | |
| SCHEMBL17624542 | 0.80 | KMT2A (0.49) | ALDH1A1SMN1; SMN2GBA1 | |
| SCHEMBL8910619 | 0.79 | PSIP1 (0.56) | PSIP1HSD11B1POLBMMP13ALDH1A1 | |
| SCHEMBL1972951 | 0.79 | PSIP1 (0.56) | PSIP1HSD11B1POLBMMP13ALDH1A1 | |
| SCHEMBL9426107 | 0.79 | PSIP1 (0.56) | PSIP1HSD11B1POLBALDH1A1TP53 | |
| SCHEMBL7724605 | 0.79 | PSIP1 (0.56) | PSIP1HSD11B1POLBALDH1A1TP53 | |
| SCHEMBL27596821 | 0.79 | PSIP1 (0.56) | PSIP1HSD11B1POLBMMP13ALDH1A1 | |
| SCHEMBL27838489 | 0.79 | HSD11B1 (0.50) | PSIP1HSD11B1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |