SCHEMBL527140

SCHEMBL527140

C=CC(N)Oc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 2/20 0.36
TSHR P16473 2/20 0.36
LTA4H P09960 1/20 0.36
DPP4 P27487 2/20 0.33
ALDH1A1 P00352 1/20 0.33
F2 P00734 1/20 0.33
MAOA P21397 1/20 0.33
CA4 P22748 1/20 0.33
POLB P06746 1/20 0.33
AOC3 Q16853 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
KDM4E B2RXH2 1/20 0.32
THRB P10828 1/20 0.32
SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9501295 0.92 MAOA (0.47) TSHRLTA4HMAOACA1CA2
SCHEMBL9507359 0.81 LMNA (0.42) TSHRLTA4HDPP4ALDH1A1MAOA
SCHEMBL326200 0.80 MAOB (0.54) LTA4HMAOACA4CA1CA2
SCHEMBL7258661 0.78 ESR2 (0.41) LTA4HALDH1A1CA4TAAR1CA1
SCHEMBL8909407 0.77 CA4 (0.39) SCN4ATSHRLTA4HDPP4MAOA
SCHEMBL6822836 0.77 CA1 (0.37) SCN4ATSHRLTA4HDPP4F2
SCHEMBL366155 0.77 CA4 (0.39) SCN4ATSHRLTA4HDPP4MAOA
SCHEMBL5186741 0.77 LMNA (0.43) ALDH1A1
SCHEMBL10607087 0.76 TSHR (0.39) TSHRLTA4HALDH1A1MAOACA4
SCHEMBL9325379 0.74 TSHR (0.38) TSHRLTA4HALDH1A1CA4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2498746-B1 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES UNILEVER PLC NO 41424 (GB) 2016-08-24 EP claimed
US-8309064-B2 Skin care compositions comprising phenoxyalkyl amines CONOPCO, INC. (US) 2012-11-13 US claimed
EP-2498746-A2 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2012-09-19 EP claimed
CN-102686212-A Skin care compositions comprising phenoxyalkyl amines UNILEVER PLC 2012-09-19 CN claimed
WO-2011054804-A2 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES UNILEVER PLC (GB) 2011-05-12 WO claimed
US-20110110870-A1 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES CONOPCO, INC., D/B/A UNILEVER (US) 2011-05-12 US claimed
WO-2010004016-A1 USE OF PHENOXYALKYLAMINES IN COSMETIC AND/OR DERMATOLOGICAL COMPOSITIONS L'OREAL (FR) 2010-01-14 WO claimed
EP-0618195-B1 Insecticidal, acaricidal and fungicidal pyrazole phenoxyalkylamin derivatives and process for preparing the same UBE INDUSTRIES (JP) 1997-06-04 EP claimed
CN-1031639-C Phenoxyalkylamine compound and its preparing method UNIV CHINA PHARMACY (CN) 1996-04-24 CN claimed
US-5409957-A Phenoxyalkylamine and agricultural and horticultural bactericide MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-04-25 US claimed
US-5039692-A Phenoxyalkylamine derivatives, and insecticides, acaricides and fungicides UBE INDUSTRIES, LTD. (JP) 1991-08-13 US claimed
EP-0429314-A2 Phenoxyalkylamine and agricultural and horticultural bactericide MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1991-05-29 EP claimed
EP-0405808-A1 Phenoxyalkylamine derivatives and insecticides, acaricides and fungicides UBE INDUSTRIES, LTD. (JP) 1991-01-02 EP claimed
EP-0186275-A2 2-Substituted amino-4(1H)-pyrimidone derivatives, their production, and medical compositions containing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-07-02 EP claimed
US-4225608-A ANTIDEPRESSANTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1980-09-30 US claimed
EP-0004288-A2 Phenoxyalkyl amines, pharmaceutical compositions containing them, and process for their preparation MERCK PATENT GmbH (DE) 1979-10-03 EP claimed
US-4038319-A SUBSTITUTED PHENOXYALKYLAMINES, PROCESS FOR THEIR PREPARATION AND APPLICATIONS THEREOF LABORATOIRES LAROCHE NAVARRON (FR) 1977-07-26 US claimed
US-3988475-A ANAESTHETICS, ANTIARRHYTHMIA, HYPOTENSIVES, ADRENERGIC ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) 1976-10-26 US claimed
US-3979456-A Phenoxyalkylamines, process for their preparation and applications thereof LABORATOIRES LAROCHE NAVARRON (FR) 1976-09-07 US claimed
US-3959359-A VASODILATORS LABORATOIRES LAROCHE NAVARRON (FR) 1976-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110110870-A1 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES CUTA, TYR, FLNA SCN4A 783/4885TSHR 4502/4885LTA4H 645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.