Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910246 | 0.78 | SIGMAR1 (0.43) | SIGMAR1HIF1AHSD11B1 | |
| SCHEMBL8910607 | 0.77 | BPTF (0.49) | SIGMAR1HIF1AHSD11B1 | |
| SCHEMBL8908776 | 0.76 | SIGMAR1 (0.41) | SIGMAR1HIF1A | |
| SCHEMBL5499445 | 0.75 | SIGMAR1 (0.47) | SIGMAR1HIF1A | |
| SCHEMBL8909808 | 0.74 | SIGMAR1 (0.53) | SIGMAR1HIF1AHSD11B1 | |
| SCHEMBL18434095 | 0.72 | HSD11B1 (0.47) | CNR2HSD11B1HTR1AL3MBTL1 | |
| SCHEMBL18434074 | 0.71 | HSD11B1 (0.44) | CNR2HSD11B1HTR1AL3MBTL1 | |
| SCHEMBL8910605 | 0.71 | SIGMAR1 (0.60) | SIGMAR1HIF1AHSD11B1 | |
| SCHEMBL8908675 | 0.69 | SIGMAR1 (0.36) | SIGMAR1CNR2HSD11B1 | |
| SCHEMBL8908767 | 0.69 | SIGMAR1 (0.46) | SIGMAR1HIF1AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658923-A | USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |