Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910097 | 0.87 | MMP13 (0.33) | MMP13ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL8124258 | 0.73 | CHRM1 (0.40) | ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL410519 | 0.72 | NOTUM (0.43) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL8124187 | 0.72 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL17653870 | 0.70 | AGBL2 (0.38) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL8123162 | 0.69 | DAO (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL410525 | 0.69 | NOTUM (0.43) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL7982124 | 0.69 | ALDH1A1 (0.34) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL411970 | 0.69 | KDM4E (0.34) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL9892806 | 0.69 | KDM4E (0.37) | MMP13ALDH1A1KDM4EMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |