Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910768 | 0.92 | DRD4 (0.39) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL8911389 | 0.85 | TSHR (0.36) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL8231306 | 0.81 | CES2 (0.42) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL8910314 | 0.69 | DRD4 (0.41) | DRD4CXCR3ALDH1A1MEN1KMT2A | |
| SCHEMBL8910772 | 0.68 | DRD4 (0.37) | DRD4DRD2CXCR3ALDH1A1MEN1 | |
| SCHEMBL3968052 | 0.67 | HTR6 (0.36) | DRD4DRD2ALDH1A1MEN1KMT2A | |
| SCHEMBL27494865 | 0.66 | FNTA (0.44) | DRD4DRD2HTT | |
| SCHEMBL8911392 | 0.65 | DRD4 (0.34) | DRD4CXCR3 | |
| SCHEMBL10669758 | 0.64 | LSS (0.62) | CHRM1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30851239 | 0.63 | CXCR4 (0.62) | CHRM1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |