Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910772 | 0.92 | DRD4 (0.37) | DRD4CXCR3KMT2AKDM4EMEN1 | |
| SCHEMBL8911392 | 0.84 | DRD4 (0.34) | DRD4CXCR3 | |
| SCHEMBL8910318 | 0.83 | HTR7 (0.43) | DRD4CXCR3KMT2AMEN1HTR7 | |
| SCHEMBL8910776 | 0.75 | HTR7 (0.42) | DRD4CXCR3KMT2AMEN1HTR7 | |
| SCHEMBL8910312 | 0.69 | DRD4 (0.41) | DRD4CXCR3KMT2AMEN1ALDH1A1 | |
| SCHEMBL8911396 | 0.67 | DRD4 (0.40) | DRD4KMT2AKDM4EMEN1HTR7 | |
| SCHEMBL8910768 | 0.66 | DRD4 (0.39) | DRD4CXCR3KMT2AMEN1ALDH1A1 | |
| SCHEMBL8911389 | 0.65 | TSHR (0.36) | DRD4CXCR3ALDH1A1MAPTHPGD | |
| SCHEMBL1321517 | 0.64 | PKM (0.55) | HTR7PKMMDM2MAPTHTR2C | |
| SCHEMBL11884861 | 0.59 | ALDH1A1 (0.47) | KMT2AKDM4EMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |