Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231306 | 0.69 | CES2 (0.42) | HTR6ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL8910312 | 0.67 | DRD4 (0.41) | ALDH1A1MEN1KMT2ACHRM3MAPT | |
| SCHEMBL8910768 | 0.67 | DRD4 (0.39) | ALDH1A1MEN1KMT2AMAPTDRD2 | |
| SCHEMBL4674919 | 0.60 | HTR6 (0.64) | HTR6SIGMAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL4675159 | 0.60 | HTR6 (0.64) | HTR6SIGMAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL4675195 | 0.60 | HTR6 (0.64) | HTR6SIGMAR1ALDH1A1MEN1KMT2A | |
| Aziridine SCHEMBL29206308 | 0.59 | SIGMAR1 (0.50) | HTR6SIGMAR1ALDH1A1GAAMEN1 | |
| SCHEMBL6781872 | 0.59 | KMT2A (0.58) | ALDH1A1MAPK1USP2GAAMEN1 | |
| SCHEMBL584720 | 0.57 | ALDH1A1 (0.69) | ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL5770320 | 0.57 | ALDH1A1 (0.69) | ALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954689-A4 | N-SUBSTITUTED-1H-QUINOLINE-2, 4-DIONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RES INST CHEM TECH (KR) | 2009-09-02 | — | — | EP | disclosed |
| EP-1954689-A1 | N-SUBSTITUTED-1H-QUINOLINE-2, 4-DIONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007032572-A1 | N-SUBSTITUTED-1H-QUINOLINE-2, 4-DIONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-03-22 | — | — | WO | disclosed |