Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.68 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.68 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.68 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.66 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.64 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.59 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.59 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911157 | 1.00 | PRKCA (0.68) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL8910329 | 1.00 | PRKCA (0.68) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL19433866 | 1.00 | PRKCA (0.68) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL18719362 | 0.92 | ENPP2 (0.71) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL2126223 | 0.92 | PRKCA (0.73) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL8911249 | 0.92 | PRKCA (0.73) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL8002666 | 0.92 | PRKCA (0.73) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL64083 | 0.91 | PRKCA (0.71) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| Choline SCHEMBL28280251 | 0.90 | PRKCA (0.56) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| Choline SCHEMBL28126920 | 0.90 | PRKCA (0.56) | PRKCAPRKCEPRKCQPRKCDENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5626867-A | LIPOSOME FOR CYTOTOXIC AGENTS | MAX-PLANCK GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 1997-05-06 | — | — | US | claimed |
| EP-0630231-B1 | LIPOSOMES WITH EXCESS NEGATIVE CHARGE | MAX PLANCK GESELLSCHAFT (DE) | 1996-03-06 | — | — | EP | claimed |
| WO-2014055505-A1 | BODIPY DYES FOR BIOLOGICAL IMAGING | THE GENERAL HOSPITAL CORPORATION (US) | 2014-04-10 | — | — | WO | disclosed |
| US-5626867-A | LIPOSOME FOR CYTOTOXIC AGENTS | MAX-PLANCK GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0630231-B1 | LIPOSOMES WITH EXCESS NEGATIVE CHARGE | MAX PLANCK GESELLSCHAFT (DE) | 1996-03-06 | — | — | EP | disclosed |