Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.73 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.73 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.73 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.70 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.65 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.65 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.65 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.65 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.65 |
| ▸ | CES2 | O00748 | 1/20 | 0.65 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.65 |
| ▸ | DGKA | P23743 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | SELP | P16109 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002666 | 1.00 | PRKCA (0.73) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL8911249 | 1.00 | PRKCA (0.73) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL64083 | 0.99 | PRKCA (0.71) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| Glycerin SCHEMBL28136461 | 0.95 | DGKA (0.70) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL30668211 | 0.94 | ENPP2 (0.75) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL2125352 | 0.93 | FAAH (0.66) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL8910338 | 0.92 | PRKCA (0.68) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL8911157 | 0.92 | PRKCA (0.68) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL8910329 | 0.92 | PRKCA (0.68) | PRKCAPRKCEPRKCQPRKCDENPP2 | |
| SCHEMBL19433866 | 0.92 | PRKCA (0.68) | PRKCAPRKCEPRKCQPRKCDENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052539-A1 | NOVEL NEUTRAL (BIO)MATERIAL | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-04-26 | — | — | WO | claimed |
| EP-2444464-A1 | Novel neutral (bio)material | Centre National de la Recherche Scientifique (CNRS) (FR) | 2012-04-25 | — | — | EP | claimed |
| WO-2012052539-A1 | NOVEL NEUTRAL (BIO)MATERIAL | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-04-26 | — | — | WO | disclosed |
| EP-2444464-A1 | Novel neutral (bio)material | Centre National de la Recherche Scientifique (CNRS) (FR) | 2012-04-25 | — | — | EP | disclosed |
| US-20100239501-A1 | GENE SENSITIVE TO BONE/JOINT DISEASE AND USE THEREOF | RIKEN (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2153847-A1 | GENE SENSITIVE TO BONE/JOINT DISEASE AND USE THEREOF | Riken (JP) | 2010-02-17 | — | — | EP | disclosed |
| US-6344342-B1 | AN ISOLATED POLYNUCLEOTIDE ENCODING A POLYPEPTIDE; DIAGNOSIS AND THERAPY FOR INFECTIONS CAUSED BY HIV-1 OR HIV-2, CANCERS, DIABETES, ASTHMA, PARKINSON'S DISEASE, ULCERS, ALLERGIES, CONGESTIVE HEART FAILURE, KIDNEY DISEASES, SEXUAL DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-02-05 | — | — | US | disclosed |
| US-6242572-B1 | AMINO ACID SEQUENCE OF POLYPEPTIDE; ANTICARCINOGENIC AGENTS; ANTIDIABETIC AGENTS; HYPOTENSIVE/HYPERTENSIVE AGENTS; ANTIULCER AGENTS; TREATMENT OF NERVOUS SYSTEM DISORDERS, SLEEP DISORDERS, GLANDULAR DISORDERS AND OTHERS; DIAGNOSIS | SMITHKLINE BEECHAM CORPORATION | 2001-06-05 | — | — | US | disclosed |