Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | BAD | Q92934 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910380 | 0.88 | NPC1 (0.33) | ACHEMCHR1NPC1RAB9A | |
| SCHEMBL8912125 | 0.84 | HDAC1 (0.33) | — | |
| SCHEMBL8910792 | 0.82 | TAAR1 (0.39) | MCHR1 | |
| SCHEMBL8912610 | 0.80 | PDE4A (0.38) | KDM4E | |
| SCHEMBL8910431 | 0.73 | ESR2 (0.35) | NPC1RAB9A | |
| SCHEMBL8912193 | 0.72 | PLAU (0.35) | KDM4ENPC1RAB9A | |
| SCHEMBL7224610 | 0.71 | KDM4E (0.40) | ACHEKDM4ENPC1RAB9A | |
| SCHEMBL7328025 | 0.66 | RAB9A (0.47) | ACHEHTR2BKDM4ENPC1RAB9A | |
| SCHEMBL7496643 | 0.66 | RAB9A (0.47) | ACHEHTR2BKDM4ENPC1RAB9A | |
| SCHEMBL6614159 | 0.62 | NPC1 (0.67) | BCL2L1BADKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |