Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911974 | 0.76 | ALDH1A1 (0.30) | MAPTKMT2A | |
| SCHEMBL7098420 | 0.76 | HTR2C (0.45) | MEN1MAPTKMT2A | |
| SCHEMBL8910299 | 0.69 | CYP17A1 (0.33) | — | |
| SCHEMBL8910677 | 0.69 | CYP17A1 (0.33) | — | |
| SCHEMBL8911274 | 0.66 | CA12 (0.37) | NPC1 | |
| SCHEMBL10428642 | 0.63 | HTR2C (0.47) | MEN1MAPTKMT2A | |
| SCHEMBL8910440 | 0.62 | — | — | |
| Acridine SCHEMBL28511403 | 0.61 | MAPT (0.71) | NQO2MEN1NPC1USP2POLB | |
| SCHEMBL8910990 | 0.60 | — | — | |
| SCHEMBL23558663 | 0.58 | HSD11B1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608065-A | ADAMANTANEOSPIRO-HETEROAROMATIC PYRANS | OPTISCHE WERKE G. RODENSTOCK (DE) | 1997-03-04 | — | — | US | claimed |