Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098420 | 0.78 | HTR2C (0.45) | HTTTSHR | |
| SCHEMBL8912772 | 0.75 | MAPT (0.38) | HTTSMN1; SMN2 | |
| SCHEMBL7300235 | 0.70 | CA12 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8910299 | 0.70 | CYP17A1 (0.33) | — | |
| SCHEMBL8910677 | 0.70 | CYP17A1 (0.33) | SMN1; SMN2 | |
| SCHEMBL8910451 | 0.69 | P2RX7 (0.31) | — | |
| SCHEMBL8912778 | 0.69 | TP53 (0.30) | — | |
| SCHEMBL16359971 | 0.68 | HTR2C (0.39) | CA12CA1CA2CA9CHRNB2 | |
| SCHEMBL1115250 | 0.67 | HTR2C (0.41) | CA12CA1CA2CA9 | |
| SCHEMBL8910432 | 0.66 | NQO2 (0.33) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608065-A | ADAMANTANEOSPIRO-HETEROAROMATIC PYRANS | OPTISCHE WERKE G. RODENSTOCK (DE) | 1997-03-04 | — | — | US | claimed |