Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 8/20 | 0.66 |
| ▸ | DRD1 | P21728 | 5/20 | 0.66 |
| ▸ | DRD4 | P21917 | 4/20 | 0.66 |
| ▸ | DRD5 | P21918 | 4/20 | 0.66 |
| ▸ | DRD3 | P35462 | 3/20 | 0.66 |
| ▸ | DRD2 | P14416 | 2/20 | 0.65 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910594 | 1.00 | HRH1 (0.66) | HRH1DRD1DRD4DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL8909022 | 0.99 | HRH1 (0.65) | HRH1DRD1DRD4DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL8909029 | 0.99 | HRH1 (0.65) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL8773759 | 0.91 | LTA4H (0.64) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL8911278 | 0.88 | ALDH1A1 (0.61) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL8911288 | 0.88 | ALDH1A1 (0.61) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL8873974 | 0.84 | SLC6A1 (0.58) | SLC6A1 | |
| SCHEMBL8873964 | 0.84 | SLC6A1 (0.58) | SLC6A1 | |
| SCHEMBL8872620 | 0.83 | SLC6A1 (0.60) | SLC6A1 | |
| Hydrochloric Acid SCHEMBL8871874 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635518-A | TREATING CENTRAL NERVOUS SYSTEM AILMENT RELATED TO 4-AMINOBUTYRIC ACID UPTAKE | NOVO NORDISK A/S (DK) | 1997-06-03 | — | — | US | claimed |
| EP-0705247-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1996-04-10 | — | — | EP | claimed |
| WO-1995000485-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1995-01-05 | — | — | WO | claimed |