Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5054625 | 0.73 | GPR3 (0.41) | HPGDPLA2G10ALDH1A1LMNAKDM4E | |
| SCHEMBL891151 | 0.71 | HPGD (0.44) | HPGDPLA2G10ALDH1A1LMNAKDM4E | |
| SCHEMBL891024 | 0.70 | GPR3 (0.39) | HPGDPLA2G10ALDH1A1LMNAKDM4E | |
| SCHEMBL12624661 | 0.70 | GPR3 (0.46) | PLA2G10ALDH1A1GPR3L3MBTL1ACLY | |
| SCHEMBL13477890 | 0.68 | PTPN1 (0.42) | HPGDPLA2G10ALDH1A1GPR3MAPT | |
| SCHEMBL11367086 | 0.67 | HPGD (0.59) | HPGDLMNATSHRMAPTMEN1 | |
| SCHEMBL14522095 | 0.67 | PLA2G10 (0.36) | HPGDPLA2G10ALDH1A1LMNAKDM4E | |
| SCHEMBL14963692 | 0.66 | GPR3 (0.41) | HPGDALDH1A1LMNAKDM4EGPR3 | |
| SCHEMBL1193910 | 0.65 | ALDH1A1 (0.44) | HPGDPLA2G10ALDH1A1LMNAKDM4E | |
| SCHEMBL1535958 | 0.65 | ALDH1A1 (0.44) | PLA2G10ALDH1A1LMNAKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722076-B2 | Photochrome- or near IR dye-coupled polymeric matrices for medical articles | SURMODICS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | BANK OF MONTREAL, AS COLLATERAL AGENT | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | IK, PIR, PLOD1 | HPGD 1754/4885PLA2G10 2771/4885ALDH1A1 2674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.