Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 6/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283349 | 0.83 | SLC15A1 (0.44) | — | |
| SCHEMBL27356477 | 0.83 | SLC15A1 (0.44) | — | |
| SCHEMBL7340739 | 0.76 | EPHX1 (0.47) | TRPA1 | |
| SCHEMBL7426334 | 0.75 | TRPA1 (0.44) | TRPA1CPA1DPP4DPP7FAP | |
| SCHEMBL6168501 | 0.75 | DPP4 (0.44) | TRPA1CPA1DPP4DPP7DPP8 | |
| SCHEMBL28128396 | 0.72 | TRPA1 (0.58) | TRPA1LOXL2 | |
| SCHEMBL1239401 | 0.70 | TRPA1 (0.50) | TRPA1CPA1DPP4DPP7LOXL2 | |
| SCHEMBL27682472 | 0.70 | TRPA1 (0.50) | TRPA1CPA1DPP4DPP7LOXL2 | |
| SCHEMBL5749249 | 0.70 | TRPA1 (0.47) | TRPA1LOXL2 | |
| SCHEMBL28034061 | 0.70 | TRPA1 (0.47) | TRPA1CPA1DPP4DPP7LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |