Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912222 | 0.90 | OPRM1 (0.35) | LTB4R2AGTR1AGTR2SLC6A2SLC6A4 | |
| SCHEMBL8912399 | 0.90 | FFAR4 (0.34) | FFAR4 | |
| SCHEMBL8911748 | 0.90 | MEN1 (0.34) | FFAR4SLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL9080394 | 0.89 | LTB4R2 (0.34) | LTB4R2 | |
| SCHEMBL8488367 | 0.89 | AGTR1 (0.37) | LTB4R2FFAR4AGTR1AGTR2 | |
| SCHEMBL8911298 | 0.89 | NPSR1 (0.33) | FFAR4 | |
| SCHEMBL8813016 | 0.88 | LTB4R2 (0.33) | LTB4R2FFAR4 | |
| SCHEMBL8482137 | 0.88 | AGTR1 (0.43) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL8912327 | 0.87 | AGTR1 (0.41) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL8483446 | 0.87 | AGTR1 (0.43) | LTB4R2AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620998-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| US-5506240-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |