Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GYS1 | P13807 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911748 | 0.98 | MEN1 (0.34) | NPSR1MEN1KMT2APOLBFFAR4 | |
| SCHEMBL8811839 | 0.89 | NPSR1 (0.32) | NPSR1MEN1KMT2APOLBGYS1 | |
| SCHEMBL9079958 | 0.89 | TSHR (0.33) | NPSR1MEN1KMT2ANR1H4ALDH1A1 | |
| SCHEMBL8910698 | 0.89 | LTB4R2 (0.35) | FFAR4 | |
| SCHEMBL8912399 | 0.88 | FFAR4 (0.34) | FFAR4 | |
| SCHEMBL8912222 | 0.87 | OPRM1 (0.35) | — | |
| SCHEMBL8812028 | 0.87 | MEN1 (0.33) | MEN1KMT2AGYS1FFAR4LMNA | |
| SCHEMBL8486729 | 0.87 | MEN1 (0.35) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL8482778 | 0.86 | MEN1 (0.35) | NPSR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8488367 | 0.86 | AGTR1 (0.37) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620998-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| US-5506240-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |