Phthalic Acid

Phthalic Acid

SCHEMBL891070

C=C(C)C(=O)OCC.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
MAPT P10636 2/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
TSHR P16473 2/20 0.52
ALOX15 P16050 1/20 0.48
TDP1 Q9NUW8 3/20 0.45
GAA P10253 2/20 0.45
HSD17B10 Q99714 2/20 0.45
THRB P10828 1/20 0.44
KDM4E B2RXH2 1/20 0.43
ESR1 P03372 1/20 0.43
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43
HMGB1 P09429 1/20 0.43
HPGD P15428 1/20 0.43
GGT1 P19440 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
BLM P54132 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL674394 1.00 ALDH1A1 (0.54) ALDH1A1MAPTMEN1KMT2ATSHR
Phthalic Acid SCHEMBL4599263 0.88 TDP1 (0.51) ALDH1A1KMT2ATSHRALOX15TDP1
Phthalic Acid SCHEMBL4826245 0.88 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2ATSHR
Phthalic Acid SCHEMBL28743573 0.87 MEN1 (0.61) ALDH1A1MAPTMEN1KMT2ATSHR
Phthalic Acid SCHEMBL3317643 0.87 ALDH1A1 (0.54) ALDH1A1MEN1KMT2ATSHRALOX15
Biphenyl SCHEMBL27587021 0.86 MAPT (0.57) ALDH1A1MAPTMEN1KMT2ATSHR
Benzene SCHEMBL29271689 0.85 THRB (0.57) ALDH1A1MAPTMEN1KMT2ATSHR
Benzene SCHEMBL7154663 0.85 THRB (0.57) ALDH1A1MAPTMEN1KMT2ATSHR
Phenol SCHEMBL6136311 0.84 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2ATSHR
Phenol SCHEMBL6751269 0.84 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3471831-B1 ONE PART ACRYLIC NAIL FORMULATION MYCONE DENTAL SUPPLY CO INC (US) 2026-01-07 EP claimed
EP-2475725-B2 REMOVABLE COLOR GEL BASECOAT FOR ARTIFICIAL NAIL COATINGS AND METHODS THEREFORE BRANDCO CND 2020 LLC (US) 2023-08-02 EP claimed
EP-3402461-B1 NAIL COMPOSITION WITH CAPPED OLIGOMERS REVLON CONSUMER PROD CORP (US) 2021-12-01 EP claimed
CN-108463209-B Nail compositions with end-capped oligomers 露华浓消费品公司 2021-09-17 CN claimed
EP-3029114-B1 SYSTEM FOR COVERING A NAIL SURFACE CREATIVE NAIL DESIGN INC (US) 2021-03-03 EP claimed
US-10632060-B2 Nail composition with capped oligomers REVLON CONSUMER PRODUCTS CORPORATION (US) 2020-04-28 US claimed
US-20200113810-A9 Nail Composition with Capped Oligomers MUFG BANK LTD. AS AGENT 2020-04-16 US claimed
US-20190151222-A1 ONE PART ARTIFICIAL NAIL SCULPTING COMPOSITIONS AND METHODS WITHOUT REACTIVE OLIGOMERS NAIL ALLIANCE, LLC 2019-05-23 US claimed
US-20190151223-A1 ONE PART ARTIFICIAL NAIL COMPOSITIONS MYCONE DENTAL SUPPLY CO INC (US) 2019-05-23 US claimed
US-20190125652-A1 One Part Acrylic Nail Formulation MYCONE DENTAL SUPPLY CO INC (US) 2019-05-02 US claimed
US-8367742-B2 Removable color layer for artificial nail coatings and methods therefore CREATIVE NAIL DESIGN, INC. (US) 2013-02-05 US claimed
WO-2012121704-A1 COMPOSITIONS AND METHODS FOR UV-CURABLE COSMETIC NAIL COATINGS CREATIVE NAIL DESIGN, INC. (US) 2012-09-13 WO claimed
EP-2486067-A1 REMOVABLE PROTECTIVE TOPCOAT FOR ARTIFICIAL NAIL COATINGS AND METHODS THEREFORE Creative Nail Design, Inc. (US) 2012-08-15 EP claimed
EP-2486068-A1 REMOVABLE COLOR LAYER FOR ARTIFICIAL NAIL COATINGS AND METHODS THEREFORE Creative Nail Design, Inc. (US) 2012-08-15 EP claimed
US-20120083547-A1 REMOVABLE COLOR LAYER FOR ARTIFICIAL NAIL COATINGS AND METHODS THEREFORE Creative Nail Disign, Inc. (US) 2012-04-05 US claimed
US-20110274633-A1 COMPOSITIONS AND METHODS FOR UV-CURABLE COSMETIC NAIL COATINGS COLOMER USA (US) 2011-11-10 US claimed
WO-2011043879-A1 REMOVABLE PROTECTIVE TOPCOAT FOR ARTIFICIAL NAIL COATINGS AND METHODS THEREFORE CREATIVE NAIL DESIGN, INC. (US) 2011-04-14 WO claimed
WO-2011043880-A1 REMOVABLE COLOR LAYER FOR ARTIFICIAL NAIL COATINGS AND METHODS THEREFORE CREATIVE NAIL DESIGN, INC. (US) 2011-04-14 WO claimed
US-20110081306-A1 REMOVABLE COLOR LAYER FOR ARTIFICIAL NAIL COATINGS AND METHODS THEREFORE CREATIVE NAIL DESIGN, INC. (US) 2011-04-07 US claimed
US-20110082228-A1 REMOVABLE PROTECTIVE TOPCOAT FOR ARTIFICIAL NAIL COATINGS AND METHODS THEREFORE CREATIVE NAIL DESIGN, INC. (US) 2011-04-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190151223-A1 ONE PART ARTIFICIAL NAIL COMPOSITIONS POLR1C, PIK3C3, NACA ALDH1A1 3782/4885MAPT 298/4885MEN1 554/4885
US-20190151222-A1 ONE PART ARTIFICIAL NAIL SCULPTING COMPOSITIONS AND METHODS WITHOUT REACTIVE OLIGOMERS POLR1C, NACA, SUCLG1 ALDH1A1 2608/4885MAPT 111/4885MEN1 466/4885
US-20190125652-A1 One Part Acrylic Nail Formulation POLR1C, NACA, PIK3C3 ALDH1A1 321/4885MAPT 85/4885MEN1 580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.