SCHEMBL5267430

SCHEMBL5267430

O=C(O)c1ccc(OC2(Oc3ccc(C(=O)O)c(C(=O)O)c3)C=CC(C(=O)c3ccccc3)C=C2)cc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.48
PYGM P11217 6/20 0.40
PYGL P06737 5/20 0.40
ALDH1A1 P00352 2/20 0.40
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HPSE Q9Y251 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GALK1 P51570 1/20 0.36
CASP6 P55212 1/20 0.36
MCL1 Q07820 1/20 0.36
PLEC Q15149 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
PGR P06401 1/20 0.36
CYP2D6 P10635 1/20 0.36
HPGD P15428 1/20 0.36
SLC6A2 P23975 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4649899 0.89 POLB (0.39) POLBPYGMPYGLALDH1A1CDC25A
SCHEMBL8911079 0.83 HTT (0.36) POLBALDH1A1HSD17B10MCL1LMNA
SCHEMBL10893912 0.82 TDP1 (0.42) POLBALDH1A1TDP1HPGDMAPK1
SCHEMBL1627984 0.80 MAOA (0.36) LMNAHTTL3MBTL1
SCHEMBL9750703 0.79 PBRM1 (0.42) POLBALDH1A1LMNASLC6A2PDE4A
Ammonia Solution, Strong SCHEMBL10582921 0.78 MAOA (0.35) LMNAHTTL3MBTL1
SCHEMBL6537068 0.75 AKR1C3 (0.37) POLBALDH1A1HSD17B10KDM4ETDP1
SCHEMBL210844 0.72 TSHR (0.41) ALDH1A1HSD17B10LMNACYP1A2HPGD
SCHEMBL4675279 0.72 PYGL (0.36) POLBPYGMPYGLALDH1A1CDC25A
SCHEMBL5927265 0.72 MAPT (0.36) POLBALDH1A1KDM4ETDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1828283-A2 POLYCARBONATE-ULTEM BLOCK COPOLYMERS General Electric Company (US) 2007-09-05 EP disclosed
WO-2006066055-A2 POLYCARBONATE-ULTEM BLOCK COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2006-06-22 WO disclosed
EP-1303571-B1 POLYIMIDE HYBRID ADHESIVES 3M INNOVATIVE PROPERTIES CO (US) 2004-05-26 EP disclosed
EP-1303571-A1 POLYIMIDE HYBRID ADHESIVES 3M Innovative Properties Company (US) 2003-04-23 EP disclosed
WO-2002004572-A1 POLYIMIDE HYBRID ADHESIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO disclosed
US-6294259-B1 EPOXY COMPONENT, AN EPOXY CURING AGENT, AND AN ENDCAPPED POLYIMIDE OLIGOMER FROM 4,4'-BIS(3,4-DICARBOXYPHENOXY)BISPHENOL A AND M-PHENYLENEDIAMINE 3M INNOVATIVE PROPERTIES COMPANY 2001-09-25 US disclosed
EP-0186243-B1 IMPACT MODIFIED POLYETHERIMIDE-POLYCARBONATE BLENDS GENERAL ELECTRIC COMPANY (US) 1993-02-03 EP disclosed
US-5166246-A Resistance to water absorption and swelling by adding a phenolic compound to the blend GENERAL ELECTRIC COMPANY (US) 1992-11-24 US disclosed
EP-0315025-A1 Amide-imide copolymers and process for the preparation thereof GENERAL ELECTRIC COMPANY (US) 1989-05-10 EP disclosed
EP-0303598-A1 POLYETHERIMIDE-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1989-02-22 EP disclosed
US-4772653-A Stain resistant cookware from blends comprising an interpolymer of an unsaturated dicarboxylic acid compound AMOCO CORPORATION (US) 1988-09-20 US disclosed
WO-1988006170-A1 POLYETHERIMIDE-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1988-08-25 WO disclosed
US-4673708-A WITH ACRYLIC RUBBER GENERAL ELECTRIC COMPANY (US) 1987-06-16 US disclosed
EP-0224696-A2 Flame retardant polyetherimide-polycarbonate blends GENERAL ELECTRIC COMPANY (US) 1987-06-10 EP disclosed
US-4629759-A BROMINATED POLYSTYRENE AND-OR ACRYLIC RUBBER COMPOSITE GENERAL ELECTRIC COMPANY (US) 1986-12-16 US disclosed
EP-0186243-A2 Impact modified polyetherimide-polycarbonate blends GENERAL ELECTRIC COMPANY (US) 1986-07-02 EP disclosed
US-4585852-A MELT POLYMERIZATION GENERAL ELECTRIC COMPANY (US) 1986-04-29 US disclosed
EP-0120184-A2 Continuous process for preparing polyetherimides GENERAL ELECTRIC COMPANY (US) 1984-10-03 EP disclosed