Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405973 | 0.94 | MMP13 (0.39) | MMP13 | |
| SCHEMBL7409438 | 0.94 | MMP13 (0.39) | MMP13 | |
| SCHEMBL7405969 | 0.94 | MMP13 (0.39) | MMP13 | |
| SCHEMBL501931 | 0.82 | MMP13 (0.41) | MMP13SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7513515 | 0.80 | MMP13 (0.40) | MMP13 | |
| SCHEMBL2577927 | 0.80 | SLC6A3 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7407540 | 0.77 | HTR6 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5802609 | 0.76 | FKBP1A (0.36) | — | |
| SCHEMBL7366077 | 0.73 | KMT2A (0.41) | MMP13 | |
| SCHEMBL7412821 | 0.73 | KMT2A (0.41) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771319-A1 | TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996002542-A1 | TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |