Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912581 | 0.90 | CYP11B1 (0.37) | CYP11B1CYP11B2KMT2AMCHR1MEN1 | |
| SCHEMBL8911251 | 0.89 | FFAR1 (0.39) | CYP11B1CYP11B2KMT2AMCHR1MEN1 | |
| SCHEMBL8912130 | 0.83 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AMCHR1MEN1 | |
| SCHEMBL8912511 | 0.79 | CYP11B1 (0.42) | CYP11B1CYP11B2KMT2AMEN1ROCK2 | |
| SCHEMBL8910893 | 0.79 | CYP11B1 (0.38) | CYP11B1CYP11B2KMT2AMCHR1MEN1 | |
| SCHEMBL8911137 | 0.78 | GCGR (0.36) | CYP11B1CYP11B2KMT2AMCHR1NR1H2 | |
| SCHEMBL8912795 | 0.78 | EPHX2 (0.41) | CYP11B1CYP11B2KMT2AMCHR1MEN1 | |
| SCHEMBL8911515 | 0.78 | CYP11B1 (0.41) | CYP11B1CYP11B2KMT2AMCHR1MEN1 | |
| SCHEMBL8912807 | 0.77 | CYP11B1 (0.44) | CYP11B1CYP11B2KMT2AMEN1ROCK2 | |
| SCHEMBL8911120 | 0.77 | NR1H2 (0.35) | CYP11B1CYP11B2MCHR1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |