Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911085 | 0.90 | CYP11B1 (0.37) | CYP11B1CYP11B2GCGRKMT2AFFAR1 | |
| SCHEMBL8911251 | 0.90 | FFAR1 (0.39) | CYP11B1CYP11B2KMT2AFFAR1MCHR1 | |
| SCHEMBL8911137 | 0.88 | GCGR (0.36) | CYP11B1CYP11B2GCGRCHEK1CYP19A1 | |
| SCHEMBL8912130 | 0.84 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AMCHR1MAPT | |
| SCHEMBL8912511 | 0.80 | CYP11B1 (0.42) | CYP11B1CYP11B2KMT2AEP300MEN1 | |
| SCHEMBL8911515 | 0.79 | CYP11B1 (0.41) | CYP11B1CYP11B2KMT2AMCHR1MAPT | |
| SCHEMBL8912795 | 0.79 | EPHX2 (0.41) | CYP11B1CYP11B2KMT2AMCHR1MAPT | |
| SCHEMBL8912807 | 0.78 | CYP11B1 (0.44) | CYP11B1CYP11B2KMT2AEP300MEN1 | |
| SCHEMBL8911120 | 0.78 | NR1H2 (0.35) | CYP11B1CYP11B2GCGRFFAR1MCHR1 | |
| SCHEMBL8912183 | 0.77 | KMT2A (0.40) | CYP11B1CYP11B2KMT2AMCHR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |