Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3594428 | 0.77 | CYP2C19 (0.41) | CHRM3ALDH1A1PAX8HTR2CSLC6A4 | |
| SCHEMBL27488088 | 0.75 | FABP5 (0.41) | — | |
| SCHEMBL8726223 | 0.74 | KMT2A (0.39) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2949855 | 0.72 | CYP2C9 (0.44) | CTSKCTSSALDH1A1PAX8MAPT | |
| SCHEMBL8911121 | 0.72 | CYP2C9 (0.44) | CTSKCTSSALDH1A1PAX8MAPT | |
| SCHEMBL73588 | 0.72 | DAO (0.43) | CHRM3ALDH1A1DAOCHRM2CHRM1 | |
| SCHEMBL1163820 | 0.71 | PAX8 (0.41) | GBA1CTSKCTSSCHRM3RIPK1 | |
| SCHEMBL3553060 | 0.70 | CTSK (0.44) | CTSKCTSSMAPTSMN1; SMN2 | |
| SCHEMBL4004775 | 0.70 | CTSK (0.44) | CTSKCTSSMAPTSMN1; SMN2 | |
| SCHEMBL7951407 | 0.69 | SLC6A4 (0.40) | CTSKCTSSALDH1A1HTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169833-A | Analgesics | G. D. SEARLE & CO. (US) | 1992-12-08 | — | — | US | disclosed |