Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LGMN | Q99538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913629 | 0.88 | ALDH1A1 (0.57) | CTSKMAPTNPSR1TP53POLB | |
| SCHEMBL8907072 | 0.87 | CTSK (0.48) | CTSKMAPTNPSR1LMNAHTT | |
| SCHEMBL8908693 | 0.87 | CTSK (0.48) | CTSKMAPTNPSR1LMNAHTT | |
| SCHEMBL8907299 | 0.87 | CTSK (0.48) | CTSKMAPTNPSR1LMNAHTT | |
| SCHEMBL8913894 | 0.86 | MEN1 (0.48) | CTSKMAPTNPSR1LMNATP53 | |
| SCHEMBL8911455 | 0.81 | CAPN1 (0.45) | CTSKMAPTTP53RXFP1POLB | |
| SCHEMBL8907102 | 0.81 | CTSK (0.49) | CTSKLMNAHTTALDH1A1MEN1 | |
| SCHEMBL8912016 | 0.77 | CNR2 (0.52) | CTSKMAPTNPSR1LMNACTSS | |
| SCHEMBL11055593 | 0.72 | MEN1 (0.61) | CTSKMAPTLMNACTSSCTSL | |
| SCHEMBL2949041 | 0.72 | CTSK (0.57) | CTSKLMNACTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799230-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019482-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |