Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PTPRF | P10586 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPA | Q15257 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913629 | 0.84 | ALDH1A1 (0.57) | CTSKMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8907299 | 0.82 | CTSK (0.48) | CTSKMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8907072 | 0.82 | CTSK (0.48) | CTSKMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8908693 | 0.82 | CTSK (0.48) | CTSKMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8907957 | 0.82 | PRKCZ (0.44) | CTSKMEN1KMT2AATMKDM4E | |
| SCHEMBL8913894 | 0.81 | MEN1 (0.48) | CTSKMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8911355 | 0.81 | CTSK (0.48) | CTSKMEN1KMT2AALDH1A1HTT | |
| SCHEMBL11415968 | 0.78 | CTSK (0.56) | CTSKMEN1KMT2AATMCYP1A2 | |
| SCHEMBL12414363 | 0.77 | LMNA (0.49) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL8911455 | 0.77 | CAPN1 (0.45) | CTSKMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799230-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019482-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |