Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913894 | 0.87 | MEN1 (0.48) | CAPN1CAPN2POLBCTSKMEN1 | |
| SCHEMBL8913629 | 0.84 | ALDH1A1 (0.57) | POLBCTSKMEN1KMT2AALDH1A1 | |
| SCHEMBL8908693 | 0.83 | CTSK (0.48) | POLBCTSKMEN1KMT2AALDH1A1 | |
| SCHEMBL8907299 | 0.83 | CTSK (0.48) | POLBCTSKMEN1KMT2AALDH1A1 | |
| SCHEMBL8907072 | 0.83 | CTSK (0.48) | POLBCTSKMEN1KMT2AALDH1A1 | |
| SCHEMBL8911355 | 0.81 | CTSK (0.48) | POLBCTSKMEN1KMT2AALDH1A1 | |
| SCHEMBL8907102 | 0.77 | CTSK (0.49) | CTSKMEN1KMT2AALDH1A1 | |
| SCHEMBL8912016 | 0.73 | CNR2 (0.52) | CNR2POLBCTSKMEN1KMT2A | |
| SCHEMBL8911772 | 0.71 | ATM (0.48) | — | |
| SCHEMBL8908677 | 0.70 | CTSK (0.52) | CTSKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799230-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019482-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |