Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911492 | 1.00 | HCRTR1 (0.55) | HCRTR1POLBHTTALDH1A1MMP8 | |
| SCHEMBL3728863 | 0.88 | HCRTR1 (0.65) | HCRTR1POLBHTTMMP8MMP12 | |
| SCHEMBL5185239 | 0.84 | HCRTR1 (0.61) | HCRTR1POLBHTTALDH1A1MMP8 | |
| SCHEMBL3722693 | 0.83 | POLB (0.58) | HCRTR1POLBHTTALDH1A1MMP8 | |
| SCHEMBL27932411 | 0.83 | POLB (0.58) | HCRTR1POLBHTTALDH1A1MMP8 | |
| SCHEMBL31717377 | 0.81 | HTT (0.53) | HCRTR1POLBHTTALDH1A1MMP8 | |
| SCHEMBL5062486 | 0.81 | HTT (0.53) | POLBHTTALDH1A1MMP8MMP12 | |
| SCHEMBL3727147 | 0.81 | MMP8 (0.58) | POLBHTTALDH1A1MMP8MMP12 | |
| SCHEMBL3720830 | 0.81 | L3MBTL1 (0.60) | POLBHTTALDH1A1MMP8MMP12 | |
| SCHEMBL2705837 | 0.78 | HCRTR1 (0.64) | HCRTR1HTTKDM4ETSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591854-A | CATALYTIC CONDENSATION OF DIENES AND VINYLDIAZOMETHANEESTERS | WAKE FOREST UNIVERSITY (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1996011928-A1 | ENANTIOSELECTIVE SYNTHESIS OF SEVEN-MEMBERED CARBOCYCLES AND TROPANES | WAKE FOREST UNIVERSITY (US) | 1996-04-25 | — | — | WO | disclosed |