Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TXN | P10599 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240421 | 0.87 | NPC1 (0.77) | NPC1RAB9APOLBMAPTHTT | |
| SCHEMBL4094573 | 0.84 | NFKB1 (0.61) | NPC1RAB9APOLBMAPTNFKB1 | |
| SCHEMBL13654063 | 0.83 | NFKB1 (0.57) | NPC1RAB9APOLBMAPTHTT | |
| SCHEMBL14388020 | 0.83 | POLB (0.93) | POLBMAPTNFKB1MEN1KMT2A | |
| SCHEMBL6673841 | 0.83 | CA12 (0.57) | POLBMAPTNFKB1MEN1KMT2A | |
| SCHEMBL8518925 | 0.82 | MEN1 (0.68) | NPC1RAB9APOLBMAPTHTT | |
| SCHEMBL28316334 | 0.81 | CA1 (0.55) | NPC1RAB9APOLBMAPTNFKB1 | |
| SCHEMBL11837292 | 0.81 | NFKB1 (0.78) | NPC1RAB9APOLBMAPTNFKB1 | |
| SCHEMBL304437 | 0.81 | POLB (0.63) | NPC1RAB9APOLBMAPTNFKB1 | |
| SCHEMBL18516810 | 0.81 | NPC1 (0.68) | NPC1RAB9APOLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652327-A | Triazine polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |
| EP-0668529-A2 | Triazine polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-23 | — | — | EP | disclosed |