Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 9/20 | 0.78 |
| ▸ | CNR2 | P34972 | 3/20 | 0.74 |
| ▸ | CNR1 | P21554 | 1/20 | 0.74 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169654 | 0.88 | TAS2R14 (1.00) | TAS2R14MEN1KMT2A | |
| SCHEMBL1279281 | 0.88 | TAS2R14 (1.00) | TAS2R14MEN1KMT2A | |
| SCHEMBL984791 | 0.87 | TAS2R14 (0.71) | TAS2R14CNR2MEN1KMT2AMAPT | |
| SCHEMBL20393926 | 0.84 | ALDH1A1 (0.64) | TAS2R14CNR2CNR1KCNA5MEN1 | |
| SCHEMBL1615817 | 0.83 | TAS2R14 (1.00) | TAS2R14MEN1KMT2A | |
| SCHEMBL14470114 | 0.83 | KMT2A (0.70) | TAS2R14CNR2CNR1MEN1KMT2A | |
| SCHEMBL1169700 | 0.83 | TAS2R14 (0.75) | TAS2R14CNR2CNR1MEN1KMT2A | |
| SCHEMBL4243334 | 0.82 | BACE1 (0.71) | TAS2R14CNR2MEN1KMT2AMAPT | |
| SCHEMBL4413527 | 0.82 | HTR2A (0.75) | TAS2R14CNR2CNR1MEN1KMT2A | |
| SCHEMBL12863088 | 0.82 | CXCR3 (0.74) | TAS2R14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670508-A | ANTITUMOR AGENTS FOR BRAIN TUMORS | NATIONAL SCIENCE COUNCIL (TW) | 1997-09-23 | — | — | US | disclosed |