Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | DHFR | P00374 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911693 | 0.77 | TTR (0.47) | NOS1DHFRGFERXDHPOLB | |
| SCHEMBL8912282 | 0.72 | DRD4 (0.43) | NOS1DHFRXDH | |
| SCHEMBL25886493 | 0.70 | GFER (0.49) | GFERPOLBCYP2C9CYP2C19KMT2A | |
| SCHEMBL17066447 | 0.68 | KMT2A (0.55) | POLBMEN1KMT2A | |
| SCHEMBL8631458 | 0.67 | HRH3 (0.50) | CYP2C9CYP2C19MAPK1 | |
| SCHEMBL27383717 | 0.67 | SIGMAR1 (0.54) | POLBMEN1KMT2A | |
| SCHEMBL25543294 | 0.67 | PARP1 (0.40) | MEN1KMT2A | |
| SCHEMBL2510973 | 0.66 | KMT2A (0.50) | MEN1KMT2A | |
| SCHEMBL29261428 | 0.66 | KMT2A (0.49) | CYP2C19MEN1KMT2AMAPK1 | |
| SCHEMBL30689041 | 0.66 | KMT2A (0.39) | POLBCYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670508-A | ANTITUMOR AGENTS FOR BRAIN TUMORS | NATIONAL SCIENCE COUNCIL (TW) | 1997-09-23 | — | — | US | disclosed |