Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | MYC | P01106 | 4/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912282 | 0.81 | DRD4 (0.43) | NOS1DHFRXDHALDH1A1CYP1A2 | |
| SCHEMBL8912815 | 0.77 | TSHR (0.57) | TSHRALDH1A1 | |
| SCHEMBL8048603 | 0.74 | ALDH1A1 (0.61) | MYCTSHRNR4A1MLYCDPOLB | |
| SCHEMBL8912435 | 0.74 | DHFR (0.40) | NOS1DHFRGFERXDHPOLB | |
| SCHEMBL8913183 | 0.71 | DHFR (0.44) | NOS1DHFRGFERXDHPOLB | |
| SCHEMBL594621 | 0.70 | L3MBTL1 (0.57) | MYCNR4A1POLBNPC1ENPP2 | |
| SCHEMBL3808106 | 0.68 | ALDH1A1 (0.70) | MYCTSHRNR4A1POLBNPC1 | |
| SCHEMBL29467270 | 0.68 | NPC1 (0.68) | MYCTSHRNR4A1POLBNPC1 | |
| SCHEMBL2492855 | 0.68 | NPC1 (0.68) | MYCTSHRNR4A1POLBNPC1 | |
| SCHEMBL9114338 | 0.68 | ALDH1A1 (0.58) | MYCTSHRNR4A1ENPP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670508-A | ANTITUMOR AGENTS FOR BRAIN TUMORS | NATIONAL SCIENCE COUNCIL (TW) | 1997-09-23 | — | — | US | disclosed |