SCHEMBL891244

SCHEMBL891244

CCCCCC1=CC(=O)C=CC1=O

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.96
BACE1 P56817 1/20 0.96
ALOX5 P09917 15/20 0.51
PTGS2 P35354 5/20 0.51
GLS2 Q9UI32 1/20 0.50
PTPN1 P18031 1/20 0.46
STAT3 P40763 1/20 0.44
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
MPEG1 Q2M385 7/20 0.40
XIAP P98170 2/20 0.40
GPR84 Q9NQS5 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
PTGES O14684 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28564810 0.98 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL10701374 0.98 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL31203727 0.98 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL3264783 0.98 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL20875697 0.98 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL10704172 0.98 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL11018415 0.98 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL10702354 0.98 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL8782213 0.98 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL28549544 0.98 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11311548-B2 Cancer therapy ASLAN PHARMACEUTICALS PTE. LTD. (SG) 2022-04-26 US claimed
CN-110496163-A The preparation method of citrous bud or flower or branch or leaf or fruit active component or ingredient and its application in medicine preparation UNIV JIANGXI TRADITIONAL CHINESE MEDICINE 2019-11-26 CN claimed
CN-108524511-A Cancer therapy 阿斯兰制药有限公司 2018-09-14 CN claimed
EP-0418278-A1 PROCESS FOR THE PREPARATION OF (ARYLETHYL)HYDROQUINONES AND DIESTERS THEREOF EASTMAN KODAK COMPANY (US) 1991-03-27 EP claimed
WO-1989012037-A1 PROCESS FOR THE PREPARATION OF (ARYLETHYL)HYDROQUINONES AND DIESTERS THEREOF EASTMAN KODAK COMPANY (US) 1989-12-14 WO claimed
US-20240307472-A1 BEVERAGES CONTAINING NATURAL PRODUCTS PK Beverages LLC (US) 2024-09-19 US disclosed
US-20240245623-A1 MODULAR TRANSDERMAL DELIVERY SYSTEM AND ASSOCIATED METHODS OF MANUFACTURE AND USE PURE RATIOS HOLDING INC (US) 2024-07-25 US disclosed
CN-117659025-A TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2024-03-08 CN disclosed
CN-117586108-A TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2024-02-23 CN disclosed
CN-117586191-A TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2024-02-23 CN disclosed
CN-111542515-B TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2023-12-05 CN disclosed
CN-116999424-A Acyl quinic acid compound and application thereof 陕西中医药大学 2023-11-07 CN disclosed
US-4306012-A Process of radiation and heat treatment of printing medium HERCULES INCORPORATED (US) 1981-12-15 US disclosed
EP-0038092-A1 Photographic material suited for use in diffusion transfer photography AGFA-GEVAERT N.V. (BE) 1981-10-21 EP disclosed
US-4272610-A LITHOGRAPHIC PLATES HERCULES INCORPORATED (US) 1981-06-09 US disclosed
US-4271259-A Photosensitive compositions containing a photooxidizable component HERCULES INCORPORATED (US) 1981-06-02 US disclosed
US-4198238-A Photopolymerizable composition HERCULES INCORPORATED (US) 1980-04-15 US disclosed
US-4174218-A CROSSLINKING ADDITION POLYMER WITH SATURATED MONOMER BY PHOTOPOLYMERIZATION HERCULES INCORPORATED (US) 1979-11-13 US disclosed
US-4137081-A Printing plates from polymer with terminal unsaturation HERCULES INCORPORATED (US) 1979-01-30 US disclosed
US-4047963-A ETHYLENE OXIDE COPOLYMER, UNSATURATED MONOMER, PHOTOINITIATOR HERCULES INCORPORATED (US) 1977-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11311548-B2 Cancer therapy DHODH, MCL1, DOHH ACHE 3770/4885BACE1 3979/4885ALOX5 2190/4885
US-20240307472-A1 BEVERAGES CONTAINING NATURAL PRODUCTS FABP3, SIRT3, SIRT5 ACHE 3320/4885BACE1 3612/4885ALOX5 2533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.