Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 5/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912034 | 0.98 | RAB9A (0.41) | RAB9ATPMTERCC5FEN1FABP4 | |
| SCHEMBL8911364 | 0.85 | DDR1 (0.40) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL8912782 | 0.76 | RAB9A (0.36) | RAB9ATPMTERCC5FEN1FABP4 | |
| SCHEMBL10560273 | 0.73 | RAB9A (0.41) | RAB9ATPMTERCC5FEN1FABP4 | |
| SCHEMBL8913304 | 0.72 | VNN1 (0.40) | GAAGSK3B | |
| SCHEMBL8912916 | 0.71 | DDR1 (0.38) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL2644679 | 0.71 | TPMT (0.56) | RAB9ATPMTERCC5FEN1FABP4 | |
| SCHEMBL12788976 | 0.70 | TPMT (0.48) | RAB9ATPMTERCC5FEN1FABP4 | |
| SCHEMBL1198757 | 0.69 | GSK3B (0.61) | RAB9ATPMTFABP4GSK3BHCAR1 | |
| SCHEMBL10364574 | 0.68 | NPSR1 (0.49) | RAB9AFABP4P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0317275-A2 | Control of ectoparasites | BRITISH TECHNOLOGY GROUP USA INC. (US) | 1989-05-24 | — | — | EP | disclosed |