Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 9/20 | 0.38 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | RHOC | P08134 | 5/20 | 0.35 |
| ▸ | RHOA | P61586 | 5/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911364 | 0.87 | DDR1 (0.40) | DDR1SLC13A3ACLYMEN1PLA2G1B | |
| SCHEMBL8911694 | 0.75 | CES2 (0.41) | GAARHOCRHOAP2RX1CES2 | |
| SCHEMBL766063 | 0.74 | GSK3B (0.56) | DDR1SLC13A3ACLYMEN1PLA2G1B | |
| SCHEMBL8912629 | 0.74 | GSK3B (0.30) | — | |
| SCHEMBL8912034 | 0.73 | RAB9A (0.41) | MEN1PLA2G1BCYP1A2CYP3A4GAA | |
| SCHEMBL8912782 | 0.71 | RAB9A (0.36) | MEN1KMT2A | |
| SCHEMBL8912642 | 0.71 | RAB9A (0.40) | MEN1PLA2G1BCYP1A2CYP3A4GAA | |
| SCHEMBL27873685 | 0.71 | DDR1 (0.48) | DDR1SLC13A3ACLYMEN1PLA2G1B | |
| SCHEMBL8913304 | 0.70 | VNN1 (0.40) | DDR1GAACES2HDAC3HDAC1 | |
| SCHEMBL23091832 | 0.68 | CES2 (0.64) | GAARHOCRHOAP2RX1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |