Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 5/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911364 | 0.83 | DDR1 (0.40) | CES2DDR1HDAC3HDAC1HDAC2 | |
| SCHEMBL10875582 | 0.79 | P2RX1 (0.40) | CES2PTPN1GAA | |
| SCHEMBL865889 | 0.77 | PTPN1 (0.58) | VNN1CES2DDR1RXRARXRB | |
| SCHEMBL8912052 | 0.75 | PLOD2 (0.42) | VNN1CES2DDR1RXRARXRB | |
| SCHEMBL6925102 | 0.73 | CES2 (0.47) | VNN1CES2DDR1RXRARXRB | |
| SCHEMBL10874474 | 0.73 | GAA (0.43) | CES2PTPN1GSK3BGAA | |
| Hydrochloric Acid SCHEMBL15732661 | 0.72 | CES2 (0.46) | VNN1CES2DDR1RXRARXRB | |
| SCHEMBL23091832 | 0.72 | CES2 (0.64) | CES2RXRARXRBRXRGHDAC3 | |
| SCHEMBL28050273 | 0.71 | RXRA (0.43) | VNN1CES2DDR1RXRARXRB | |
| SCHEMBL27757817 | 0.70 | CES2 (0.56) | VNN1CES2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |