Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.42 |
| ▸ | FCER2 | P06734 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 4/20 | 0.36 |
| ▸ | MC3R | P41968 | 4/20 | 0.36 |
| ▸ | MC5R | P33032 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | MC1R | Q01726 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316964 | 1.00 | GHSR (0.42) | GHSRFCER2TACR1MMEACE | |
| SCHEMBL6316746 | 0.94 | MMP1 (0.41) | GHSRFCER2TACR1MMP9MC4R | |
| SCHEMBL6319166 | 0.90 | PTPN1 (0.38) | GHSRTACR1MMP9MMP8MC4R | |
| SCHEMBL6319672 | 0.89 | GHSR (0.44) | GHSRTACR1MMP9MMP8KLKB1 | |
| SCHEMBL6320709 | 0.89 | CYP1A2 (0.39) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL6324396 | 0.86 | GHSR (0.46) | GHSRFCER2TACR1MMP9MMP8 | |
| SCHEMBL6320145 | 0.85 | TACR1 (0.39) | TACR1MMP9MMP8KLKB1 | |
| SCHEMBL6324563 | 0.85 | MMP3 (0.43) | MMP9KLKB1 | |
| SCHEMBL6326078 | 0.84 | S1PR1 (0.39) | TACR1MMP9MMP8KLKB1 | |
| SCHEMBL6323403 | 0.84 | CTSS (0.46) | GHSRFCER2MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |