Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 6/20 | 0.54 |
| ▸ | PRKCG | P05129 | 6/20 | 0.54 |
| ▸ | PRKCB | P05771 | 6/20 | 0.54 |
| ▸ | PRKCA | P17252 | 6/20 | 0.54 |
| ▸ | PRKCH | P24723 | 6/20 | 0.54 |
| ▸ | PRKCI | P41743 | 6/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 6/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.54 |
| ▸ | PRKD1 | Q15139 | 6/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | PRKACA | P17612 | 4/20 | 0.54 |
| ▸ | PRKACG | P22612 | 4/20 | 0.54 |
| ▸ | PRKACB | P22694 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913820 | 0.90 | PRKD3 (0.53) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8914458 | 0.85 | P2RX7 (0.50) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8912770 | 0.82 | ROCK2 (0.53) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9397203 | 0.81 | PRKD3 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8914327 | 0.80 | CYP3A4 (0.48) | CYP3A4CYP2C19KDM4ECYP1A2CYP2D6 | |
| SCHEMBL9398259 | 0.78 | PRKD3 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8913812 | 0.77 | ROCK2 (0.51) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL9398501 | 0.76 | PRKD3 (0.60) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL10553061 | 0.75 | PRKD3 (0.52) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8915393 | 0.75 | ALDH1A1 (0.51) | HTTTSHRHSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663174-A | ANTIINFLAMMATORY AGENTS, INHIBITOR OF KINASES, ANTIARTHRITIC AGENTS | PHARNO-WEDROPHARM GMBH (DE) | 1997-09-02 | — | — | US | disclosed |
| EP-0602028-B1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARNO WEDROPHARM GMBH (DE) | 1996-01-17 | — | — | EP | disclosed |