Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049827 | 0.85 | DRD2 (0.54) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL3605711 | 0.83 | ADRB1 (0.65) | ADRA1DADRA1AADRA1BHTR1AADRB1 | |
| Hydrochloric Acid SCHEMBL5365168 | 0.82 | ADRB1 (0.63) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5223815 | 0.82 | ADRB1 (0.63) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL6583554 | 0.81 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL8123524 | 0.80 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL13533012 | 0.79 | DRD2 (0.58) | HTR1A | |
| SCHEMBL27237957 | 0.79 | PARP1 (0.48) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL3610680 | 0.79 | ADRB1 (0.58) | ADRA1DADRA1AADRA1BADRB1 | |
| SCHEMBL6582397 | 0.78 | HTR1A (0.49) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628039-B1 | 2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF | NOVO NORDISK AS (DK) | 1997-05-02 | — | — | EP | disclosed |
| US-5470850-A | Central nervous system disorders | NOVO NORDISK A/S (DK) | 1995-11-28 | — | — | US | disclosed |